Christian Eriksen should start against Aston Villa as Tottenham begin the new season in front of their own fans for the first time in almost a decade.
The Dane's future is very much uncertain with less than 12 months to run on his contract and many European windows still open until the end of the month.
Lucas Moura, who signed a new contract on the eve of the new season, and talisman Harry Kane are expected to complete the front three. Injured Dele Alli and suspended Heung-min Son are unavailable.
Club-record signing Tanguy Ndombele will make his competitive debut and should be partnered in midfield by Moussa Sissoko and Harry Winks. Eric Dier and Victor Wanyama are back in training.
Ben Davies is still some weeks away from a return after undergoing surgery on a groin injury, so Danny Rose should start at left-back. New signing Ryan Sessegnon is still recovering from an injury sustained with England Under-21s in June.
Kyle Walker-Peters should start at right-back with Juan Foyth suspended, and Kieran Trippier now an Atletico Madrid player. Serge Aurier is available but lacking match fitness.
Aston Villa, club captain James Chester is out with a hamstring problem. Douglas Luiz, a summer buy from Manchester City, is available after earning a work permit while Wesley, Matt Targett, Jota, Ezri Konsa and Trezeguet could all make their debuts.
Tottenham XI: Lloris; Walker-Peters, Alderweireld, Vertonghen, Rose; Ndombele, Sissoko, Winks; Lucas, Eriksen; Kane.
