Unai Emery has left Mesut Ozil and top score Pierre-Emerick Aubameyang on the bench for today’s north London derby.
The Arsenal boss has opted for a four-man defence which sees Shkodran Mustafi line-up at right back, alongside Sokratis Papastathopoulos, Laurent Koscielny and Nacho Monreal.
Lucas Torreira is also named among the substitutes, with Granit Xhaka partnering Matteo Guendouzi in midfield, with Aaron Ramsey, Alex Iwobi, Henrikh Mkhitaryan supporting Alexander Lacazette in attack.
Tottenham boss Mauricio Pochettino, meanwhile, welcomes back Victor Wanyama to their starting line-up for the first time since November, as the Kenyan partners Moussa Sissoko in midfield. Harry Winks misses out completely with a hip injury.
Jan Vertonghen also returns to the defence after being passed fit to play having missed the midweek defeat to Chelsea, and he partners Belgian compatriot Toby Alderweireld and Davinson Sanchez. Danny Rose and Kieran Trippier will attack from the full-back positions.
Up top, Harry Kane is joined in attack by Heung-min Son and Christian Eriksen.
Tottenham vs Arsenal line-ups
Tottenham XI: Lloris; Trippier, Alderweireld, Sanchez, Vertonghen, Rose; Wanyama, Sissoko; Eriksen, Son, Kane
Substitutes: Gazzaniga, Aurier, Davies, Skipp, Lamela, Lucas, Llorente
Arsenal XI: Leno; Mustafi, Sokratis, Koscielny, Monreal; Guendouzi, Xhaka; Mkhitaryan, Ramsey, Iwobi; Lacazette
Substitutes: Cech, Maitland-Niles, Kolasinac, Torreira, Suarez, Ozil, Aubameyang
