Tottenham's hopes of a Premier League top-four finish were dented as Wolves twice fought back from behind to win 3-2 in north London.
January signing Steven Bergwijn had put Spurs ahead early on at Tottenham Hotspur Stadium, but Matt Doherty levelled things for Nuno Espirito Santo's visitors.
A fine finish from Serge Aurier on the stroke of half-time sent Spurs in ahead at the interval, though Doherty turned provider as Diogo Jota equalised 12 minutes after the restart.
With Spurs pushing forward for a winner, Wolves broke at pace with 17 minutes remaining: Jota found Raul Jimenez, who turned Japhet Tanganga and finished well to had the visitors the lead for the first time.
Lacking the injured Harry Kane and Heung-min Son, Jose Mourinho's Spurs had no answer and fell to a damaging defeat in their bid for Champions League qualification.
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