Tottenham boss Nuno Espirito Santo is set to pick his third starting XI at the club for the pre-season season friendly at MK Dons.
Spurs, who will wear their new away kit for the first time, know Stadium MK well, having used it as a home ground once during their Wembley tenancy when the national stadium was unavailable for a Carabao Cup match against Watford.
Espirito Santo is expected to change up his squad slightly for the third friendly match of his tenure, with more than 14,000 tickets already sold for the game.
Some of the academy players who have been involved in the first two games of the Portuguese's tenure were selected in the U23s win at Hastings United on Tuesday night.
Kallum Cesay, Brooklyn Lyons-Foster, Jamie Bowden and Alfie Devine all started the match, having got minutes under Espirito Santo during one or both of the first team friendlies at Leyton Orient or Colchester.
Dane Scarlett, Nile John, Tobi Omole, Maksim Paskotsi, Troy Parrott, Harvey White, Malachi Fagan-Walcott were not involved for the U23s, which suggests most of them could travel with the first team squad to Milton Keynes.
Spurs are also now at the stage where first team players will be getting fitter and able to take on more minutes in matches, while other international players start to return to training, including Hugo Lloris and Ben Davies.
A number of players are yet to play their first game of the Espirito Santo era for varying reasons, with Matt Doherty and Sergio Reguilon among those potentially in line to get their first minutes under the Portuguese on Wednesday night.
New goalkeeper Pierluigi Gollini is now out of isolation following his move to the club, but is understood to be awaiting his work permit.
It's always tough to predict a line-up in pre-season but here is our stab at the Tottenham starting XI to face MK Dons:
(4-2-3-1) Lloris; Doherty, Tanganga, Davies, Reguilon; Skipp, John; Lucas, Alli, Bergwijn, Son.
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