Tottenham can jump ahead of Liverpool in the Premier League table on Thursday evening by collecting all three points in north London.
Just over a month since the last meeting between the teams at Anfield, Jose Mourinho's side will be looking to gain revenge for that late 2-1 defeat on Merseyside courtesy of Roberto Firmino's header.
The Reds have only won once in the league since then - the 7-0 demolition of Crystal Palace - and Spurs will be hoping to inflict even more misery on the reigning champions after such a poor run of form.
Three points will in fact see Tottenham jump into fourth and pass West Ham and Liverpool in the table, thus leaving them five points off leaders Man City in the process.
But who exactly will Mourinho select to ensure his team come out on top in the crunch clash?
Following Monday evening's 4-1 win over Wycombe Wanderers in the FA Cup, the head coach will make wholesale changes to his XI.
Hugo Lloris, who was left out completely at Adams Park, will return between the sticks and Eric Dier will also come straight back into defence following his rest on Monday.
Lining up with a three-man defence and wing-backs last time out in the league at Sheffield United, Mourinho is likely to revert to a back four as Sergio Reguilon is out with a muscle injury.
Serge Aurier will start at right-back, with Mourinho having a decision to make over Japhet Tanganga if Ben Davies isn't fit enough to start on the opposite flank.
As well as Joe Rodon did at Bramall Lane, experience is going to be vital this evening and that may see Toby Alderweireld get the nod alongside Dier instead.
Harry Winks will be in with a shout after starring against Wycombe, but Mourinho is likely to favour Moussa Sissoko next to Pierre-Emile Hojbjerg due to what he can offer off the ball against Liverpool.
Spurs' eye-catching front four of Steven Bergwijn, Tanguy Ndombele, Son Heung-min and Harry Kane complete the Tottenham XI.
Here is the team that we reckon Mourinho will choose to face Liverpool.
4-2-3-1: Lloris; Aurier, Alderweireld, Dier, Davies; Hojbjerg, Sissoko; Bergwijn, Ndombele, Son; Kane.
