Tottenham return to Premier League action on Sunday afternoon as Man City make the trip to north London.
It's a vitally important game for Jose Mourinho's men in the top-four race and they can move to within three points of Chelsea in fourth providing they lose at Leicester City a day earlier.
Mourinho is going to need his squad fully fit and firing over the remaining 14 league games as they look to leapfrog their rivals and clinch a place in Europe's elite competition for the fifth year on the trot.
Handed good news on the injury front in recent weeks with Hugo Lloris returning to action from the dislocated elbow he sustained at Brighton & Hove Albion at the start of October, Tanguy Ndombele could also come into contention for a starting spot against City after taking his place on the bench in the last two games.
However, the game will once again come too soon for left-back Ben Davies.
The Welshman was named in the starting XI for Mourinho's first match in charge at West Ham but he was forced off in the closing stages with an ankle injury.
Davies has yet to take to the pitch since for the Lilywhites and he is currently still undergoing rehabilitation on the issue.
Harry Kane and Moussa Sissoko also remain out due to hamstring and knee injuries respectively as they continue their rehabilitation.
The former is expected to return to training with the rest of the first team at Hotspur Way at some point in April, with the latter pencilled in to be back on the training pitch at the start of April.