Tottenham could ring in the changes for Saturday's Premier League trip to Leicester City but manager Mauricio Pochettino said the decision had nothing to do with their Champions League clash with Barcelona in midweek.
Spurs travel to Barcelona next Tuesday needing a win to qualify for the last 16 of the Champions League for the third time, but Pochettino said his immediate focus was on keeping pace with Liverpool and Manchester City in the league.
"We're going to try to take the best decision for Saturday, to try to be competitive and perform in the best way. It is not easy of course, because to play every three days is so tough for the players and the staff," Pochettino told reporters on Friday.
"Next is Barcelona and we are going to maybe rotate some players, because they need rest, not because we are going to play in Barcelona Tuesday.
Jan Vertonghen is back in the squad for the trip to Leicester but fellow defenders Kieran Trippier and Juan Foyth are ruled out.
Vertonghen returns following a one-match ban but Trippier has a groin problem and Foyth a hamstring issue.
Mousa Dembele (ankle), Erik Lamela (thigh), Victor Wanyama (knee) and Davinson Sanchez (hamstring) are still sidelined.
Provisional squad: Lloris, Gazzaniga, Aurier, Rose, Vertonghen, Alderweireld, Walker-Peters, Moura, Dier, Son, Alli, Kane, Eriksen, Winks, Davies, Sissoko, Llorente, Vorm.
