Lucas Moura will be missing for Tottenham in their EFL Cup semi-final first leg against Chelsea but Paulo Gazzaniga will start in goal.
Lucas picked up a knee injury in Friday's 7-0 win at Tranmere in the FA Cup and will play no part in the London derby.
The Brazilian, who scored a brace in Spurs’ 3-0 win over Manchester United earlier in the season, is also a doubt for the reverse fixture at Wembley Stadium on Sunday.
With fellow forward Heung-min Son set to join South Korean for the Asian Cup following the Premier League clash with Manchester United on January 13, Pochettino will be hoping Lucas’ absence is only short term.
Erik Lamela has recovered from illness, but Eric Dier (appendicitis) and Victor Wanyama (knee) are still out.
Furthermore, Belgian duo Jan Vertonghen and Mousa Dembele returned to training ahead of the FA Cup clash with Tranmere but did not feature and Pochettino has ruled them out of the League Cup clash.
Opponents Chelsea could welcome back attacking trio Pedro, Olivier Giroud and Willian though Ruben Loftus-Cheek is set for a spell on the sidelines due to a back problem.
