Tottenham's midfield woes show no signs of easing with Eric Dier and Harry Winks set to be ruled out of Wednesday's meeting with Crystal Palace — the club’s first senior fixture in their new £1billion stadium.
Dier is still thought to be struggling with the muscular problem that he sustained playing for England last month, while Winks has not featured since suffering a groin injury against Borussia Dortmund a month ago.
Moussa Sissoko is the only available central midfielder who has played regularly this season.
Youth product Oliver Skipp is still finding his feet in the first-team squad and Victor Wanyama has made just five starts.
Boss Mauricio Pochettino is likely to keep faith with Hugo Lloris after the 'keeper gifted Liverpool victory on Sunday.
In the final minute of the game, Lloris failed to hold a weak header from Mo Salah, palming the ball against Toby Alderweireld, who was helpless to stop the own goal.
Tottenham’s poor form — one point from their last five league fixtures — means they risk missing out on a top-four spot, even though they were involved in the title race a little more than a month ago.
Predicted XI: Lloris, Alderweireld, Sanchez, Vertonghen, Trippier, Sissoko, Eriksen, Rose, Alli, Lucas, Kane