Dele Alli and Harry Winks are both doubts for Tottenham's crunch Champions League showdown with Manchester City.
Dele fractured his left hand during Spurs' 1-0 quarter-final first-leg win over Pep Guardiola's side on Tuesday night, and has since been training with a protective cast on.
He watched Saturday's 4-0 win over Huddersfield from the stands, as did Winks after sustaining a minor groin injury during Friday's training session.
When asked about Dele's availability for City, Pochettino said: "We'll see, he's not sure. He is doing some training sessions with protection. He needs to feel comfortable.
"It's about if there's pain - it depends on the time. Today, it's difficult to know."
On Winks, Pochettino said: "He was training yesterday and in the middle of the training, he started to feel his groin. We must assess tomorrow.
"It's not a big issue, but it's an issue where he might not be able to play on Wednesday. We are optimistic but we will see."
