Tottenham return to action on Saturday lunchtime as they make the trip across the capital to face Chelsea.
The Blues haven't been in the best of form lately and Jose Mourinho's men will leapfrog them and move into the top four if they win in west London.
Losing 1-0 against RB Leipzig in the first leg of their Round of 16 Champions League clash on Wednesday evening, Spurs will be looking to bounce back in style at a ground they have really struggled at over the past 30 years.
Having lost Harry Kane and Moussa Sissoko to hamstring and knee injuries at the start of the year, the Lilywhites were dealt another major blow on Tuesday with Son Heung-min ruled out for a number of weeks due to a fracture in his right arm.
The South Korean ace actually sustained the injury in the early stages of Sunday's thrilling 3-2 win over Aston Villa but he played on and scored two crucial goals.
Son has since gone under the knife to fix the issue and at present he is recovering from surgery.
Juan Foyth is another who has joined the list of absentees in recent weeks due to a groin problem but he is now in the late stages of conditioning.
Kane and Sissoko also remain out and continue their rehabilitation from their respective injuries, with the latter now out of the gym and stepping up his return to fitness on grass.
The Lilywhites have a rare midweek off after the trip to Stamford Bridge and they face Wolves in their following fixture next Sunday.