The three remaining English sides will find out their opponents in the Europa League Round of 16 draw later today.
North London rivals Tottenham Hotspur and Arsenal feature in the draw with both sides tipped as one of the favourites to win this year's competition.
Spurs are 9/2 with Betfred after they eased through after two convincing victories over Austrian side Wolfsberger while Arsenal are 7/1 after they left it late to beat Benfica 4-3 on aggregate thanks to Pierre-Emerick Aubameyang's 87th minute winner.
The Gunners have the perfect chance to qualify for the Champions League next season if they can go one step further than in 2019 and lift the trophy.
Mikel Arteta's side lost 4-1 to Chelsea in Baku two years ago when Unai Emery was their head coach.
Meanwhile, Manchester United have been placed as the favourites by the bookies. Ole Gunnar Solskjaer's side have been priced at 5/2 after beating Real Sociedad 4-0 on aggregate.
The Red Devils lifted the trophy when Spurs boss Jose Mourinho was at the helm after beating Ajax 2-0 in Stockholm.
Meanwhile, Steven Gerrard's Rangers also feature in today's draw after two entertaining matches against Antwerp which saw the Glaswegian side win 9-5 on aggregate.
The draw will take place at 12pm.
- Manchester United - 5/2
- Tottenham - 9/2
- Arsenal - 7/1
- AC Milan - 15/2
- Ajax - 10/1
- Roma - 12/1
- Villarreal - 14/1
- Rangers - 16/1
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