The Premier League's 20 clubs will discuss the prospect of a European 'Super League' being introduced in 2024 when they meet this week.
Shareholders are set to sit down this week in Geneva at the European Club Association (ECA) and discuss a range of issues for the first time this season, with the proposals to significantly change the European calendar one of the key topics on the agenda.
England's top clubs including Manchester City and Liverpool are two of many to speak out against the proposed format change, whilst the changes would also have a huge impact on Manchester United, Chelsea, Arsenal and Tottenham.
Similarly, England's top-flight's counterparts in Spain are thought to be against the idea, with concerns about adding more fixtures to an already jam-packed schedule.
UEFA have been working closely with the European Club Association (ECA) on a proposal to redesign the prestigious European tournament from 2024, replacing it with a format featuring promotion and relegation - similarly to the UEFA Nations League - that could turn it into largely a closed competition.
The change in format would mean locking in 24 of the current 32 Champions League places, plus having eight-team groups to give clubs 14 games each that would ultimately squeeze available dates for national leagues and cups.
But the 29-nation European Leagues group says proposals include no promotion or relegation between the Champions League and Europa League from 2024 and limiting teams to six group games.
That could limit the hopes of Everton, Leicester City and Wolves, who are all hopeful of pushing the Premier League's 'big six' for a place in Europe's elite competition over the next few years.
Also amongst the topics of conversation will be the transfer window, with a number of clubs in favour of reverting England's deadline back to the end of August.
When changes were implemented last year it was expected European leagues would follow suit, with all competitions ending their transfer business before the start of their respective seasons.
However, that proved not to be the case, leaving Premier League sides vulnerable to the giants of European football, as showcased by the ongoing speculation surrounding Christian Eriksen's future this summer.
Of course, it wouldn't be a Premier League meeting without a discussion on Video Assistant Referees (VAR), which will once again be up for debate.
The technology has made a controversial entrance into the Premier League, with many feeling that there are still a number of flaws with its operation.
It is expected that the International Football Association Board's (IFAB) changes to the offside and handball rules, and how those changes have been applied, may also be up for debate, after several high-profile incidents in the opening weeks of the season.
