It was a familiar story for Spurs on Tuesday evening as one goal had a huge impact on the final result.
Looking on course to go in level 1-1 at the break after Joshua Kimmich had cancelled out Son Heung-min's early strike, Bayern Munich struck seconds before Clement Turpin blew his whistle.
Tanguy Ndombele had the chance to clear the ball away from danger but elected to take a touch in the box, it was a loose one and he went straight into Corentin Tolisso and the ball eventually broke to Robert Lewandowski who arrowed the ball into the bottom corner.
The goal proved absolutely critical.
A quickfire double from Serge Gnabry 10 minutes after the restart left Spurs with an absolute mountain to climb and it would only get worse in the final seven minutes as they added another three.
The darkest day in Mauricio Pochettino's five years at the club, it could have been oh so different had the score remained 1-1 at the break.
This is not something new as it is the third time this has happened so far this season.
Now once is perhaps a mistake and twice could be seen as a coincidence, but three times means it has now become a habit.
The first came at the start of September as Alexandre Lacazette's goal in first-half stoppage time handed Arsenal a lifeline after initially trailing 2-0.
The strike from the Frenchman was just what the Gunners needed as his partner in crime Pierre-Emerick Aubameyang made it all square with 20 minutes remaining as he found Hugo Lloris' goal with a smart finish.
Seventeen days later and the exact same happened in Greece as Spurs got their Champions League campaign up and running with a 2-2 draw against Olympiacos.
In control and 2-0 up prior to the break, Daniel Podence reduced the deficit as he ghosted between Jan Vertonghen and Ben Davies to shoot low past Lloris.
Again, just like at the Emirates, it proved vital as Mathieu Valbuena levelled from the penalty spot in the 54th minute to clinch a point for the hosts.
What can be seen from the Arsenal and Bayern Munich goals prior to half-time is that they have both come when Spurs had the chance to clear their lines and get the ball away from danger.
That never happened and Tottenham have instead paid the ultimate price.
Vertonghen stated after the game that Lewandowski's goal was a "tough one to take" and also claimed that all goals in every single game come from a mistake on the pitch.
Unfortunately, too many mistakes at the back saw Bayern inflict Spurs' heaviest ever home defeat.
It could look a lot different for Spurs in the Champions League at present had they not conceded before half-time in both games, but the goals mean that it could go down to matchday six - this time a trip to the Allianz Arena to face Bayern - as they look to make the knockout phase.
It's extremely concerning for Pochetitino's side at present and it's a habit they must kick before it causes even more issues for the team at home and Europe over the coming weeks.
