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The Cardinals’ full 2022 NFL schedule is out with 4 prime-time games

By Jess Root

The Arizona Cardinals’ 2022 regular season schedule is out. They begin the season at home against the Kansas City Chiefs and will play four prime-time games. All are home games, although one is a “home” game in Mexico City.

It is the fourth season with Kliff Kingsbury as head coach and with Kyler Murray at quarterback.

They have improved their win totals each of the last three seasons and went 11-6 in 2021, making it to the playoffs for the first time since 2015. This year, they expect more.

They will play the first six games of the season without receiver DeAndre Hopkins, who was suspended after testing positive for a banned performance-enhancing substance.

They will play their final two games of the season on the road, closing out the year against the San Francisco 49ers.

The full schedule is below.

Week Date Opponent Time (AZ)
1 Sept. 11 vs. Kansas City Chiefs 1:25 p.m. Tickets
2 Sept. 18 at Las Vegas Raiders  1:25 p.m. Tickets
3 Sept. 25 vs. Los Angeles Rams 1:25 p.m. Tickets
4 Oct. 2 at Carolina Panthers 1:05 p.m. Tickets
5 Oct. 9 vs. Philadelphia Eagles 1:25 p.m. Tickets
6 Oct. 16 at Seattle Seahawks 1:05 p.m. Tickets
7 Oct. 20 (Thursday night) vs. New Orleans Saints 5:15 p.m. Tickets
8 Oct. 30 at Minnesota Vikings 10 a.m. Tickets
9 Nov. 6 vs. Seattle Seahawks 1:05 p.m. Tickets
10 Nov. 13 at Los Angeles Rams 2:25 p.m. Tickets
11 Nov. 21 (Monday night) vs. San Francisco 49ers (in Mexico City) 5:15 p.m. Tickets
12 Nov. 27 vs. Los Angeles Chargers 2:05 p.m. Tickets
13 Dec. 4 BYE WEEK
14 Dec. 12 (Monday night) vs. New England Patriots 6:15 p.m. Tickets
15 Dec. 18 at Denver Broncos 2:05 p.m. Tickets
16 Dec. 25 (Sunday night) vs. Tampa Bay Buccaneers 6:20 p.m. Tickets
17 Jan. 1 at Atlanta Falcons 11 a.m. Tickets
18 Jan. 8 at San Francisco 49ers TBD Tickets

Listen to the latest from Cards Wire’s Jess Root on his podcast, Rise Up, See Red. Subscribe on Apple podcasts or Spotify.

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Dive Deeper:
49ers 2022 schedule: Game dates, times and tickets
Dates, times and tickets for every #49ers game in 2022!
Seattle Seahawks: Complete 2022 regular season schedule revealed
Here is Seattle's full schedule for this coming season.
Chargers’ 2022 regular season schedule revealed
Find out who, when, and where the Los Angeles Chargers will be playing during the 2022 NFL season.
Carolina Panthers 2022 regular season schedule
The Carolina Panthers' 2022 regular season schedule is officially here.
One subscription that gives you access to news from hundreds of sites
Chiefs’ 2022 regular season schedule revealed
The #Chiefs' 17-game regular-season schedule for the 2022 NFL season has officially been revealed.
2022 NFL Schedules: All 32 Teams
2022 NFL Schedules By Teams. The schedules for all 32 franchises
Get all your news in one place