Tottenham will be hoping their poor league form at the Emirates finally comes to an end on Sunday in the first north London derby of the season.
Although the team did secure a 2-0 Carabao Cup win at the home of their rivals last December, it's almost nine years since they last won there in the league as Younes Kaboul's late header capped off an incredible turnaround to clinch a 3-2 victory.
Spurs are desperate for a win on Sunday following last weekend's shock defeat to Newcastle United and they will be also looking to right the wrongs of last December when the Gunners came from behind to win 4-2.
So what can Pochettino and his side learn from that defeat after going in 2-1 up at the break?
Here we take a look...
Beware of a fast start
Arsenal really came out of the blocks at full pelt in last season's game at the Emirates as they put Spurs under relentless pressure early on.
Their start resulted in an early goal as Pierre-Emerick Aubameyang scored from the penalty spot after Jan Vertonghen's needless handball from an early corner.
The Gunners kept pushing on as they searched for a second, with Aubameyang and Alex Iwobi both having chances after good play from Sead Kolasinac.
However, the missed opportunities allowed Spurs to find a way back into the game as Son Heung-min had two attempts on goal before Eric Dier restored parity 15 minutes before the break.
Substitutes can prove crucial
Trailing 2-1 at half-time despite making such a good start, Unai Emery decided to change things around as Arsenal looked to get back on the front foot again.
Aaron Ramsey and Alexandre Lacazette replaced Henrikh Mkhitaryan and Iwobi at the break and they made a huge difference as the Gunners came from behind to win 4-2.
It was the Welshman who helped level things up as he played Aubameyang in with a clever ball as he found the net from distance to leave Hugo Lloris motionless in goal.
Ramsey then played a key role in his team's third goal as he capitalised on Juan Foyth's error to tee up Lacazette to find the back of the net.
Emery's half-time changes worked wonders and Arsenal then put the result beyond any doubt in the closing stages as Lucas Torreira scored with a low strike.
Don't make mistakes
Pochettino did spring a bit of a surprise in his starting XI by naming Foyth in the team and leaving Toby Alderweireld on the bench.
The Argentine had endured a bit of a mixed start to life in the Premier League leading up to the derby clash as he gave away two penalties at Wolves on his league debut before then scoring the winner a week later at Crystal Palace.
He was once again in the headlines for all the wrong reasons as Arsenal scored the crucial third goal having initially trailed 2-1.
A poor touch from the youngster on the halfway line saw Ramsey take full advantage to play Lacazette in to complete the turnaround.
It was a defining moment in the game and one that proved incredibly costly to his team.
Take your chances
Spurs really need to take their chances on Sunday as they aim to return to wining ways after the defeat against Newcastle.
The team could be eight points behind leaders Liverpool after only four games if they lose, while Arsenal would be five points ahead of them.
Although you cannot win the Premier League title early on, you can most definitely lose it.
Spurs did have opportunities in the first half at the Emirates through Son last year and the result may have been a lot different had he taken them.
Arsenal were always right in the game despite going in 2-1 down at the break, yet another Spurs goal in the opening 45 minutes would have given the hosts a mountain to climb in the remaining time.
Pochettino's team really do need to take their chances as in some derby clashes they are very few and far between.
