Steve Clarke will still be licking his wounds and sifting through the wreckage of Scotland's whimpering 2-0 defeat to the Czech Republic at Hampden yesterday but one obvious alteration he could make is staring him in the face.
Motherwell right-back Stephen O'Donnell is undoubtedly a decent player, and he deserves immense credit for flourishing under Clarke's guidance during our Euro 2020 qualification campaign, but even he'd admit he looked slightly out of place yesterday.
As you'd expect, Clarke's side were a constant threat down our left-hand side, with Andy Robertson constantly pinning back his opposite number, and even almost finding the back of the net on several occasions.
So, who should be given the nod on the right-hand side against England on Friday?
Here's three reasons why Clarke should shuffle the pack.
Surprise Factor
England boss Gareth Southgate is a man who does endless homework on his opposition, and he'll know all about James Forrest, O'Donnell and just about every other player in the Scotland squad.
But will he know much about Patterson? The Rangers man has played in a handful of matches for his club, never mind his country, and Southgate and co might be slightly taken aback by his electric pace and lung-bursting runs down the right-hand side.
Fearlessness
Every player in the Scotland squad will understandably be slightly daunted by the prospect of facing the Auld Enemy in their back garden - all but one, that is.
At the tender age of 19, Patterson doesn't know the meaning of the word 'fear', and considering he has just seven Premiership matches under his belt, and only one Scotland cap, he won't be held back or inhibited by any memories of previous failures or disastrous defeats.
Think of the future
Nathan Patterson is the future of Scotland's right-hand-side, plain and simply.
O'Donnell, a good player as he is, is 29 now, as is James Forrest, and this is the perfect opportunity to give Patterson a taste of the biggest stage, and hopefully make him desperate to play at this level on a regular basis.
Patterson should be let off the leash at Wembley, and show an entire continent exactly why he's one of the most exciting young prospects in the UK today.
