Superstar forward Lance Franklin will miss Sydney's huge AFL clash with Richmond due to knee soreness as the Swans count the cost of their loss to Port Adelaide.
Franklin, 36, was injured late in Saturday's heartbreaking two-point defeat to the Power and has not recovered in time to face the Tigers at Adelaide Oval on Friday.
Neither side will have their spearhead available with Richmond forward Tom Lynch (broken foot) injured and also facing suspension at the AFL tribunal.
"Lance completed the game against Port Adelaide but suffered a knock to the knee in the last quarter," Swans medical boss Damian Raper told the club's website.
"He has been unable to train this week due to his knee soreness and will not play against Richmond this weekend."
Both McCartin brothers will miss due to their respective concussions.
Luckless defender Paddy, who had nine concussions when playing for St Kilda, was substituted out of Saturday's game after a head knock that has again sparked concerns over his future.
Brother Tom, also a key defender, joined him on the sidelines with a concussion before halftime.
"Paddy is doing well in the early stages of his recovery," Raper said.
"He still has some residual symptoms which are not unexpected. He will be monitored closely in accordance with the AFL's HIA protocols.
"Tom is also doing well in his recovery but will miss the match against Richmond after entering the AFL's HIA protocols. He will continue to be monitored closely."
Forward Sam Reid has suffered a major setback in his recovery from a glute injury, dealing with hamstring tendon pain, and won't return until after the mid-season bye.
Meanwhile Carlton defender Sam Docherty will undergo surgery to repair a torn knee meniscus and will be sidelined for between four and six weeks.
Docherty's injury is a hefty blow to the unbeaten Blues given his impressive form off half-back.
"It's no doubt disappointing for Sam to be sidelined for the coming weeks, given he picked up this season right where he left off last year, in great form," Carlton football boss Brad Lloyd said.
"He's the ultimate professional though, so once he completes surgery, he'll launch into his rehab and do everything required to get back to play, which we expect to be in four to six weeks."
Former co-captain Docherty missed all of the 2018 and 2019 seasons with back-to-back ACL tears.
Docherty was diagnosed with testicular cancer in November 2020 but recovered and played the first 14 games in 2021 before a recurrence in August that year required him to undergo chemotherapy.
