Switzerland, Jamaica and the Czech Republic have been removed from the government's quarantine exemption list due to a rise in coronavirus cases.
Transport Secretary Grant Shapps announced that travellers arriving in England from those countries after 4am on Saturday will need to self-isolate for 14 days.
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The Department for Transport said equivalent measures are being put in place in Northern Ireland, Scotland and Wales.
Scotland took Switzerland off its list last week.
Mr Shapps also revealed that Cuba has been added to the list of destinations people can return from without entering quarantine.
The DfT said in a statement: "Infections from Covid-19 are on the rise across Europe.
"The Government has made consistently clear it will take decisive action if necessary to contain the virus, which includes removing countries from the travel corridors list rapidly, if the public health risk of people returning from a particular country without self-isolating becomes too high.
"This means holidaymakers may find they need to self-isolate on return to the UK and are advised to consider the implications of self-isolation on them and their families before making travel plans."
