Lee Johnson handed debuts to his newest signings, with Niall Huggins and Frederik Alves starting tonight's Carabao Cup tie at Blackpool.
Former Leeds United man Huggins - who was today named in the Wales U21 squad - lined up at right-back, while on-loan West Ham defender Alves was included at centre-back.
Another of Sunderland's new signings, on-loan Everton striker Nathan Broadhead, made his first start for the club.
Those trio were among seven changes to the side that beat AFC Wimbledon at the weekend with only four players - Anthony Patterson, Carl Winchester, Alex Pritchard and Dan Neil - retained from that starting XI.
The other players to come into the side were Dennis Cirkin, Bailey Wright, Jack Diamond, and Aiden O'Brien.
The seven who made way were Tom Flanagan, Callum Doyle, Luke O'Nien, Elliot Embleton, Lynden Gooch, Aiden McGeady, and Ross Stewart.
Blackpool boss Neil Critchley also made wholesale changes - in his case, nine from the side that drew 2-2 at Bournemouth on Saturday.
In came Dan Grimshaw, ex-Sunderland man Reece James, Sonny Carey, Shayne Lavery, Oliver Casey, CJ Hamilton, Dan Gretarsson, Cameron Antwi, and Richard Keogh, with Chris Maxwell, Callum Connolly, James Husband, Marvin Ekpiteta, Josh Bowler, Kenny Dougall, Grant Ward, Jerry Yates, and Keshi Anderson.
Tyreece John-Jules and captain Luke Garbutt were the only players retained from the weekend.
Tonight's line-ups
Sunderland: Patterson, Huggins, Alves, Wright, Cirkin, Winchester, Neil, Diamond, Pritchard, O'Brien, Broadhead
Subs: Bond, Doyle, Embleton, Gooch, Stewart, Taylor, Hawkes
Blackpool: Grimshaw, Casey, Keogh, Gretarsson, Garbutt, James, Antwi, Carey, Hamilton, Lavery, John-Jules
Subs: Moore, Husband, Yates, Anderson, Bowler, Ekpiteta, Holmes
