Phil Parkinson made five changes to the side that started the weekend FA Cup first round draw against Gillingham at the Stadium of Light.
Jon McLaughlin is away on international duty with Scotland and his place was taken by Lee Burge, who was making his comeback from the thigh injury he suffered at Shrewsbury last month.
Conor McLaughlin is away with Northern Ireland and Luke O’Nien dropped back into defence to replace him, with Grant Leadbitter filling the vacancy in midfield.
Denver Hume missed the weekend game with a virus but he returned in place of Laurens De Bock.
Duncan Watmore came in for Chris Maguire, and Marc McNulty started up front in place of Will Grigg.
Parkinson included youngsters Anthony Patterson, Benji Kimpioka, Bali Mumba, and Brandon Taylor on the bench.
boss Paul Hurst also made five changes, in his case to the side that lost at Crawley in the FA Cup on Saturday.
Jordan Clarke, Abo Eisa, Jacob Bedeau, John McAtee, and Lee Novak, came into the starting XI, in place of Andy Butler, Jamie Proctor, Yann Songo’o, Ryan Colclough, and Kevin van Veen.
Sunderland: Burge, O’Nien, Lynch, Willis, Hume, Leadbitter, Dobson, Power, Watmore, McGeady, McNulty.
Subs: Patterson, Maguire, McGeouch, De Bock, Kimpioka, Mumba, Taylor.
Scunthorpe: Eastwood, Clarke, Lund, Perch, Novak, Gilliead, McArdle, Brown, Eisa, Bedeau, McAtee.
Subs: Watson, Butler, Colclough, van Veen, Dales, Butroid, Pugh.
