A massive section of an apartment building roof came crashing down after Storm Brendan hit the UK.
Strong gales caused the damage which left a mass of wreckage in the middle of Slough High Street in Berkshire on Tuesday evening.
Dramatic photographs show construction workers looking over the rubble, with a white van trapped underneath.
Emergency services attended the scene, however Thames Valley Police said no one was believed to be injured.
They said: "We do not believe that anyone has been seriously injured, and we are working with other emergency services to make the scene safe.
"The road is closed and people are advised to avoid the area. Thank you to everyone for their ongoing patience while we deal with the incident."
Gusts in the area were in excess of 50mph at the time of the incident, according to the Met Office.
Slough Borough Council confirmed the eastern part of the High Street will remain closed on Wednesday until further notice.
Shocked onlookers shared snaps and video footage to social media.
One video shows members of the public checking to see if anyone was hurt or trapped under the rubble.
The 48-hour period of wild weather began in Ireland on Monday, causing thousands of homes to lose power, before bringing winds in excess of 80mph to parts of Scotland and England.
Airlines were forced to divert flights scheduled to land at Gatwick Airport on Monday evening while ferries and railways faced disruption.
A yellow warning of wind covering much of England expired at 5am on Wednesday, while a rain warning covering south-east England has also ceased.
Meteorologist Alex Burkill, from the Met Office, said: "It will take a little while but the rain should clear by lunchtime.
"Once it does clear away, otherwise tomorrow, most places are in for some decent sunny spells."
There could be further thundery showers mainly to the north and west of the UK, with the chance of sleet and snow across the hills and mountains of Scotland and Northern Ireland, according to the forecaster.
Mr Burkill said although the wind is due to ease off on Wednesday, conditions will still be blustery and temperatures are due to dip slightly to 9 degrees.
But he warned that more unsettled weather was forecast on Thursday, particularly during the second half of the day, when places across the country could expect wet and windy weather.
"It doesn't look as bad as what we've had through the past couple of days," he added.
"At the moment it looks like we'll stay warning free (on Thursday). It's just a windy day rather than a hazardous one."
