Sir Keir Starmer has urged Iran to return to negotiations after Donald Trump launched US air strikes on the regime’s nuclear facilities.
The Prime Minister said Iran’s nuclear programme is a “grave threat” which the US military action would “alleviate”.
There is understood to have been no UK involvement in the action, which comes after Sir Keir and Foreign Secretary David Lammy had pushed for a diplomatic solution rather than US action which could further destabilise the region.
The Prime Minister said: “Iran’s nuclear programme is a grave threat to international security.
“Iran can never be allowed to develop a nuclear weapon and the US has taken action to alleviate that threat.
“The situation in the Middle East remains volatile and stability in the region is a priority.
“We call on Iran to return to the negotiating table and reach a diplomatic solution to end this crisis.”
The US attacked three sites in Iran including the Fordo facility, which is buried deep underground.
US President Mr Trump said the key nuclear sites had been “completely and fully obliterated”.
In an address to the nation from the White House, he warned there could be further strikes if Iran retaliates: “There will either be peace or there will be tragedy for Iran.”
Iran’s nuclear programme is a grave threat to international security. Iran can never be allowed to develop a nuclear weapon and the US has taken action to alleviate that threat.
— Keir Starmer (@Keir_Starmer) June 22, 2025
The situation in the Middle East remains volatile and stability in the region is a priority. We call…
Iranian foreign minister Abbas Araghchi warned the attacks “will have everlasting consequences” and that Tehran “reserves all options” to retaliate.
The strikes followed a build-up of US military equipment, with B-2 stealth bombers – which are the only aircraft to carry a 30,000-pound bunker-buster bomb – reportedly used to target the underground facilities.
The aircraft have previously used the UK-US airbase on Diego Garcia, one of the Chagos Islands, but it is understood that was not involved in the strikes which hit Fordo, Isfahan and Natanz.
The attack on Iran also involved US submarines, which launched around 30 Tomahawk cruise missiles.
Mr Trump’s move towards military action came despite Sir Keir’s pleas for diplomacy and his repeated calls for de-escalation.
On Thursday the Prime Minister warned of a “real risk of escalation” in the conflict, adding there had previously been “several rounds of discussions” with Washington and “that, to me, is the way to resolve this issue”.
Statement by the Ministry of Foreign Affairs of the Islamic Republic of #Iran concerning the #UnitedStates military aggression against Iran's peaceful nuclear facilities
— Foreign Ministry, Islamic Republic of Iran 🇮🇷 (@IRIMFA_EN) June 22, 2025
بسم الله الرحمن الرحیم
The Ministry of Foreign Affairs of the… pic.twitter.com/GhSjSTtzx2
The Foreign Secretary urged the US to pull back from the brink on a visit to Washington for talks with counterpart Marco Rubio before heading to talks with Iran on Friday alongside European allies.
Reform UK leader Nigel Farage has backed Mr Trump’s decision to strike Iran.
He said: “Iran must not be allowed to have nuclear weapons, the future of Israel depends on it.”
Iran launched a ballistic missile barrage against Israel in retaliation to the US action.
The foreign ministry in Tehran issued a statement condemning “the United States’ brutal military aggression against Iran’s peaceful nuclear facilities”.
It added: “The Islamic Republic of Iran is resolved to defend Iran’s territory, sovereignty, security and people by all force and means against the United States’ criminal aggression.”
