A police cordon was thrown up near St Paul's Cathedral after a suspicious package was found.
City of London Police said the package had been deemed non-suspicious a little more than an hour after officers were called at 10.23am.
The object was found inside a building in St Martin's Le Grand, the force confirmed.
It said on Twitter: "The item has now been deemed non suspicious and officers are working to clear the incident. Cordons are still currently in place."
Reports on social media suggested surrounding buildings had been evacuated.
St Paul's underground station was also closed during the alert.
