Spain are almost there and face minnows Malta just a point away from clinching top spot in Group F.
La Roja are set to be one of the favourites at next summer's Euro 2020 but remain a work in progress.
Fabian Ruiz is one of the latest arrivals to the squad and appears set to attract strong interest from Real Madrid and Barcelona next summer.
While Pau Torres and Dani Olmo bring more youth as Robert Moreno shuffles the pack.
Here's everything you need to know about the game.
Team news
Adama Traore has withdrawn due to an injury, while Pau Torres and Dani Olmo are look set to make their debuts. Valencia's Rodrigo Moreno is suffering from a back problem.
Fabian Ruiz, linked with Real Madrid and Barcelona.
Alvaro Morata, Paco Alcacer and Gerard Moreno are all battling it out for a place to lead the line.
Predicted Spain XI
Kepa, Jesus Navas, Albiol, Ramos, Bernat; Busquets, Saul, Fabian, Cazorla, Oyarzabal, Alcacer
When is the match?
The match kicks off at 19:45 GMT on Friday, November 15 at the Estadio Ramon de Carranza, home of Cadiz.
How to watch?
You can watch the match in the UK on Sky Sports. You'll need to switch over on the red button to watch though.
The option to watch games on the red button is not available on Sky Go for mobile devices.
Odds
Spain 1/100
Draw 33/1
Malta 100/1
Prediction
This one is straight forward, it's how many Spain can tally up? They beat these opponents 12-1 in 1983, can they hit double figures once again?
It seems unlikely this time, Spain will look to work on other elements of their game and expect Alvaro Morata to grab at least a double in pursuit of nailing down a starting role under Moreno. Preciction: Spain 7-0 Malta.
