Newcastle United will take on the Saints knowing they can make life a hell of a lot easier for themselves going into the season's final straight.
The Magpies tweaked their formation against Burnley and West Brom and Steve Bruce is likely to do likewise at St Mary's.
United face a Saints team that have won one game in six attempts in the Premier League.
Lee Ryder's prediction
Southampton are two points ahead of Newcastle and many feel that Ralph Hasenhüttl is lucky to still be in a job after enduring some hammeriings this term.
The Austrian is under pressure after losing 3-1 at West Ham last weekend so perhaps this isn't a bad time to play them.
Given Newcastle have been boosted by the change in system and progress in the FA Cup spirits should be high.
I think they can actually surprise a few people and get an important away win.
Referee
Graham Scott (Oxfordshire)
Has taken charge of Newcastle games against Watford and Oxford.
Charity bet
Miguel Almiron to be an anytime scorer at 6/1.
