Liverpool can return to the top of the Premier League table for over a week with victory at Southampton this evening.
Manchester City's FA Cup commitments means the champions are not in Premier League action until April 14 when they travel to Crystal Palace.
Another victory - a sixth in eight games after a slight winter wobble - will see them sitting pretty before hosting Chelsea shortly after events at Selhurst Park.
The omens are good. Liverpool have won their last three against the Saints without conceding, but the hosts have turned a corner under Ralph Hasenhuttl.
Just three defeat since the turn of the year has seen Southampton move clear of relegation danger and are looking for a third home win on the trot after beating Fulham and high-flying Tottenham.
How to watch
Southampton vs Liverpool will be televised live on Sky Sports' Premier League and Main Event channels, and is available via Now TV with a day pass on offer for £8.99. Sky Sports subscribers can stream the match online via SkyGo and the SkyGo app.
You can also follow all the action with Standard Sport's LIVE blog with David Lynch at St Mary's.