Southampton will again be without forward Danny Ings for the visit of Manchester United.
On-loan Liverpool forward Ings has been carrying a hamstring problem, which saw him miss both last weekend's defeat at Fulham and the EFL Cup exit at Leicester City in midweek.
The absence of Ings – who has scored four Premier League goals since his arrival at St Mary’s in August – is a further blow to manager Mark Hughes, whose future is the subject of intense speculation as Southampton desperately attempt to end an 11-game winless run in all competitions.
England international defender Ryan Bertrand is struggling with a back issue which has kept him out of full training, so will be assessed, while striker Shane Long continues treatment on his ankle injury.
Provisional squad: McCarthy, Soares, Yoshida, Hoedt, Targett, Armstrong, Lemina, Redmond, Hojbjerg, Austin, Gabbiadini, Gunn, Vestergaard, Stephens, Davis, Elyounoussi, Ward-Prowse, Obafemi, Bertrand.