Some flights from the UK to holiday destinations such as Spain and Portugal will restart today (May 1).
Wizz Air said it will restart selected flights with "enhanced" health and safety measures due to the coronavirus pandemic.
Cabin crew will be required to wear masks and gloves on all flights and will distribute sanitising wipes for passengers, the airline said in a statement.
New distancing measures will also be introduced during boarding and aircraft will be disinfected overnight.
Today, flights will resume from the airline's base in Luton, Bedfordshire, to selected airports in Hungary, Romania, Serbia, Slovakia, Portugal, Spain and Israel.
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Owain Jones, Wizz Air UK's managing director, said: "As we restart selected Luton flights to provide an essential service to passengers who need to travel, our primary concern is the health, safety and well-being of our customers and crew.
"The protective measures that we are implementing will ensure the most sanitary conditions possible.
"We encourage our customers to watch our new video on how to stay safe when travelling, as well as for more details on our new health and safety measures."
Customers will be asked to check in and make any additional payments for services - such as additional bags - online to reduce physical interaction at the airport.
Passengers will also be "encouraged" to make any on-board purchases using contactless payment methods, the airline said.
The London-listed Hungarian company said flights will resume to:
- Budapest in Hungary
- Cluj-Napoca, Constanta, Craiova, Iasi, Suceava, Targu Mures, Satu Mare and Timisoara in Romania
- Belgrade in Serbia
- Bratislava and Kosice in Slovakia
- Lisbon in Portugal
- Tenerife in Spain's Canary Islands
- Tel Aviv in Israel.
