Scotland beat Italy 33-20 in their opener at Murrayfield - with Blair Kinghorn scoring a hat-trick - before England stunned Ireland with a 32-20 win in Dublin.
England produced a stunning performance to end Ireland's formidable home run and underline their status as serious Six Nations contenders with a remarkable bonus-point win in Dublin.
In the day's earlier game, Blair Kinghorn scored Scotland's first ever Six Nations hat-trick as they beat Italy. It is 30 years since Iwan Tukalo registered the Dark Blues' last Championship treble in a Five Nations clash with Ireland.
But Edinburgh wing Kinghorn ended that long wait as Stuart Hogg and Chris Harris also crossed over the whitewash to give Gregor Townsend's side the perfect start with a bonus point triumph.
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