Seven men have been arrested during early morning drugs raids in Rochdale, Heywood and Bury.
Police said £30,000 in cash, £18,000 of class B drugs and a Harley Davidson were also seized during the operation.
It came after nine addresses across the three towns were raided at 6am on Tuesday.
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All seven men - aged between 55 and 23 - were arrested on suspicion of conspiracy to supply class B drugs.
The raids were part of Operation Marengo targeting drug supply across Greater Manchester, Lancashire and Northern Ireland.
Det Sgt Louise Ashurst, from GMP's Serious and Organised Crime Group, said: "Today's action is a result of months of proactive and investigative work which has led to drugs and the criminal proceeds of those drugs being taken off the streets of Greater Manchester.
"The arrest and seizures are testament to the dedication put in by all of the officers involved who are helping to disrupt serious organised crime.
"The detrimental impact of serious organised criminal activity does not just impact those involved but can be felt across communities and GMP is committed to identifying this activity and ensuring those responsible face the appropriate justice.
"As always, we would ask that anyone with information or anyone with concerns to contact us as we work to disrupt serious crime across the region. Intelligence from members of the public continuously helps us with our on-going investigations - no matter how small the information may seem."
