Wales are looking to make it two wins out of two in the Six Nations when they head up to Murrayfield to take on resurgent Scotland.
But the stakes are also high for Gregor Townsend's men after their own surprise triumph over England at Twickenham.
Everything to play for then, with the winner moving just one step away from the Triple Crown and having a realistic shot at the Six Nations title.
What will happen, who emerges victorious? Our rugby experts gaze into their crystal balls....
Simon Thomas : A close call, but lineout points to Scottish win
Well, it’s fair to say it would be a good one to win from here!
Wales have been ravaged by injuries, which have ruled out five of the starting line-up from the victory over Ireland, along with a posse of other players - 21 in total, according to Wayne Pivac.
Given this, it’s pretty remarkable they are still able to field a side that boasts 865 caps and contains plenty of quality.
There’s also encouragement to be drawn from the physicality shown against the Irish, while Scotland have their own injury issues, having lost Jamie Ritchie, Cameron Redpath and Sean Maitland.
Flanker Ritchie, in particular, is a big miss for them, as he blew Wales away at the breakdown at Parc y Scarlets in October.
That, in turn, is balanced by Josh Navidi and Josh Macleod being ruled out for the visitors, reducing the red presence over the ball.
So it’s quite a tough one to call, with the two sides having firepower behind despite the missing men.
But the contrast in the efficiency of the respective lineouts just makes me edge towards Scotland.
Scotland 25-21 Wales
Ben James: Wales can nick it despite back-row imbalance
You have to wonder what is in the water down at the Vale of Glamorgan - given the number of injuries Wales are currently facing.
But Pivac must deal with the cards left in his hand and it's not a bad Wales side. They've lost a couple hundred of caps since last weekend, but it's still packed with experience.
Plus, in Willis Halaholo, they have a player on the bench who looks made for the philosophy Pivac wants to implement. The Cardiff Blues centre taking to Test rugby could be a sliding doors moment for the Wales coach.
However, I fear the back-row balance for Saturday is a little off. After Dan Lydiate and Josh Navidi, Josh Macleod was the next cab off the rank before his horrendous, cruel injury.
The reason that the uncapped Scarlets flanker was ahead of Aaron Wainwright was his style of play. Wainwright has worn the six jersey plenty of times for Wales, but he's rarely thrived alongside Taulupe Faletau.
Usually, there's been a Navidi or Ross Moriarty alongside Wainwright when he's been on song. A bit of grit to go alongside the athleticism. In truth, Faletau and Wainwright are probably a little too similar to really blend.
That could be crucial, given Wales and Scotland are largely balanced elsewhere.
The two backlines look a little blunt, but with some excellent strikerunners to create something from nothing, while the defences seem somewhat solid under the tutelage of young Welsh coaches.
If Wales can get the lineout right and somehow compensate for the back-row balance, I think they'll nick it.
Either way, I think it'll be close.
Scotland 16-18 Wales
Mark Orders: Wales still look less than the sum of their parts
There was a time when Murrayfield was known as the place Welsh hopes were wrecked, but there won’t be any supporters there this time, so, theoretically, home advantage will be neutralised.
But Wales will still do well to win.
The two sides were victorious a last weekend but Scotland were more impressive, with their pack confining England to just 35 percent of the possession at Twickenham, a day before Wales made heavy weather of putting away 14-man Ireland.
Wales looked less than the sum of their parts, with a malfunctioning lineout hindering their attempts to build momentum. They struggled to reclaim possession off Ireland, lacked creativity and found it hard to manage the game given their lack of ball.
The unavailability of Dan Lydiate or Josh Navidi will hurt them at blindside flanker and George North is a huge loss in the backs.
That said, let’s see if Scotland can back up their big performance against England. One swallow doesn’t a Six Nations make. There isn’t a lot between the sides on paper and Wales will be comfortable going to Edinburgh as underdogs.
Victory isn’t out of the question for the visitors, but they’ll need to do the basics right and find some invention behind the scrum.
The Scots played winning rugby against England, having a nice mix between running and kicking, and a six-day turnaround will not help Wales.
On balance, the odds favour Scotland — just.
Scotland 26-24 Wales
