- A new multimillion-pound study, led by the University of Dundee in collaboration with the Max Planck Institute, will investigate cellular "light switches" crucial for cell division and their role in cancer development.
- Researchers aim to decode the rhythmic signalling, known as phosphorylation-dephosphorylation (PdP) dynamics, which involves chemical tags turning proteins "on" and "off" rapidly to control cell behaviour.
- The study seeks to understand how these rapid on-off cycles, described as a "biological morse code," dictate accurate cell division and how their malfunction contributes to diseases like cancer.
- By deciphering these previously hidden signals, the team hopes to gain clearer insights into why cell division goes awry in cancer and to pave the way for more effective treatment strategies.
- The eight-year project has secured £4 million in funding from Wellcome, highlighting the significance of this research in potentially unlocking new understandings and treatments for cancer.
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