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Wales Online
Wales Online
National
Shivali Best & Neil Shaw

Scientists cure cancer in mice using technology that could work in humans

Scientists have discovered a cure for cervical cancer which works in mice using new technology and now hope to test it in humans.

Researchers from Griffith University in Australia used gene-editing technology to cure the disease - and believe it could be used in humans.

Professor Nigel McMillan, who led the study, said: “This is the first cure for any cancer using this technology.”

The team used a gene-editing tool called CRISPR-Cas9 to target and treat cervical cancer tumours via injection, using ‘stealth’ nanoparticles.

CRISPR-Cas9 can be used to cut away parts of DNA, reports The Mirror .

Professor McMillan said: “The nanoparticles search out the cancer-causing gene in cancer cells and ‘edit it’ by introducing some extra DNA that causes the gene to be misread and stop being made.

“This is like adding a few extra letters into a word, so the spell checker doesn’t recognise it ‘anyTTmore’. Because the cancer must have this gene to produce, once edited the cancer dies.

“In our study, the treated mice have 100% survival and no tumours.

"The mice showed no other clinical signs such as inflammation from treatment but there may be other gene changes we haven’t measured yet.

“Other cancers can be treated once we know the right genes.”

The technology has only been tested on mice so far, and it remains unclear if it will have the same effect in humans. Researchers say that they’re working towards human trials of the gene therapy ‘in the next five years.’

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