Alok Jha is joined by Guardian science correspondent Ian Sample and Observer science editor Robin McKie to discuss the most significant science stories of 2012. They talk about the discovery of a Higgs-like particle, the successful landing of the Curiosity rover on Mars, the creation of a mutant strain of the H5N1 bird flu virus, Arctic ice-cap melt and the Encode project mapping our genome.
Also find out what to expect in 2013, beginning with the genome editing project wrapping up clinical trials in the US in January and how it may redefine our ability to fight diseases.
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