Chelsea can face one of five teams in the Champions League round of 16, including Maurizio Sarri's Juventus and former foes Bayern Munich, Barcelona and Paris Saint-Germain.
Frank Lampard's team could also be paired with RB Leipzig and Bayern Munich when the draw is made next Monday after the young Blues saw off the challenge of Lille at Stamford Bridge to progress from Group H in second position.
First-half goals from Tammy Abraham and Cesar Azpilicueta paved the way for Chelsea, although Loic Remy ensured a nervy ending by scoring against his former club with 12 minutes remaining.
Chelsea saw the game out, however, for their first home win in the competition this season and they will be paired one of those five group winners in the round of 16.
A possible meeting against Sarri's Juve would be mouth-watering for many supporters, although RB Leipzig appears the least daunting proposition on paper.
Chelsea have plenty of history with Barca and PSG in this competition, and also defeated Bayern in Munich to win their only Champions League in 2012.
Lampard's side will play the first leg at home having finished second in the group and they cannot be drawn against other Premier League sides at this stage.
Valencia topped the pool thanks to a 1-0 win away to Ajax in Amsterdam, meaning that last year's semi-finalists have bowed out.
The Blues' immediate attention will turn to the Premier League, though, with a home game against Bournemouth to come on Saturday.
Having lost three of their past four in the league, three points is a necessity against Eddie Howe's strugglers.
