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Benzinga
Benzinga
Technology
Vandana Singh

Sarepta Abandons Lysogene-Partnered Pivotal-Stage Gene Therapy Candidate

Sarepta Therapeutics Inc (NASDAQ:SRPT) is walking away from a three-year licensing pact for a rare disease gene therapy candidate, leaving its former partner on its own as it prepares for a pivotal readout in mid-year.

  • According to Lysogene, Sarepta returned the global commercial rights for LYS-SAF302 after “unsuccessful discussions for transferring back to Lysogene the responsibility for the global commercial supply of LYS-SAF302.”
  • Sarepta paid Lysogene $15 million for ex-Europe rights to a gene therapy against the neurodegenerative lysosomal storage disorder mucopolysaccharidosis type IIIA in 2018. 
  • The deal included up to $125 million in milestones.
  • Paris-based Lysogene expects to have data from the study around the middle of the year. 
  • In a statement, Lysogene said the termination follows unsuccessful discussions about the transfer of the responsibility for global commercial supply. 
  • Sarepta took on responsibility for producing the gene therapy, including in Lysogene’s territory, as part of the 2018 deal. 
  • According to Lysogene, the partners then discussed Sarepta returning the supply responsibility but disagreed.
  • Price Action: SRPT shares are down 0.65% at $73.47 during the market session on the last check Thursday.
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