England captain Owen Farrell will miss the Premiership’s big return this weekend.
The fly-half is suffering from a tight quadricep and as a result Saracens did not want to risk him for Saturday's match with Bristol Bears.
Full-back Elliot Daly misses out too with a tight hamstring and captain Brad Barritt is absent as he is being managed back to full fitness after a long break.
But Saracens, who are already relegated, have otherwise named a strong side and five players who played in last year’s World Cup final all start, with Vincent Koch, Jamie George and Mako Vunipola making up the front-row.
Maro Itoje starts at lock and Billy Vunipola completes a formidable pack after being giving the nod at No8.
In the backs, Alex Goode will start at fly-half in the absence of Farrell and he will be paired with scrum-half Richard Wigglesworth.
