The Dick Johnson Racing driver set the tone for the race at the start, a flawless getaway allowing him to sweep right to the racing line for the first left-hander.
Fellow front-row start Shane van Gisbergen, meanwhile, was slightly sluggish off the line and was forced to head to the inside to defend from the chasing pack.
Davison immediately settled into an eighth-tenth lead over his Kiwi rival, which steadily grew to more than a second as the first stint wore on.
On Lap 17 van Gisbergen took his mandatory service, effectively forcing Davison to follow suit a lap later to limit the undercut.
The response proved to be the right one, Davison emerging well clear of van Gisbergen after taking his stop.
He then put in an impressive second stint to stretch the advantage to 8.4s by the chequered flag.
Having won his last two races after post-race penalties were applied to another competitor, this was the first time Davison crossed the finish line first to win a race since 2015.
"I crossed the finish line first, which is nice," he said. "It was a dream run. I'm privileged to have a race like that.
"I'm pushing hard, feeling good. I've been around for a while and when you have a race like that and a car like that... a huge shout-out to [engineer] Rich [Harris] and the whole Shell V-Power team."
Van Gisbergen held on to second place after staving off a brief challenge from an early-stopping Anton De Pasquale after serving his stop.
That Lap 12 stop for Feeney helped him jump Will Brown, who had run third in the early stages.
Brown, who stopped on Lap 17, came under significant pressure from a hard-charging Cam Waters later in the stint.
Waters, coming from 12th on the grid, had already barged his way past the likes of Tickford teammates Thomas Randle and James Courtney.
He couldn't get past Brown, though, the Erebus ace defending hard to finish fourth.
Randle came home ninth as Chaz Mostert completed the best 10.
The big mover of the race was David Reynolds, who used an early stop and an undercut to make up 12 positions to finish 12th.
"It's not a bad job. My car was pretty good," said Reynolds. "The unfortunate part was I didn't have any lock lights or shift lights. As a driver you really need those tools. All considered, it was a really good job."
Teammate Lee Holdsworth, however, went the other way, finishing 24th after stalling on his way out of the pit box.
Despite finishing second van Gisbergen was able to extend his series lead over De Pasquale to 401 points.
The Sandown SuperSprint continues with two back-to-back qualifying sessions starting at 10:55am local time.
|1||17||Will Davison||Ford Mustang GT|
|2||97||Shane van Gisbergen||Holden Commodore ZB||8.492||8.492|
|3||11||Anton De Pasquale||Ford Mustang GT||9.018||0.525|
|4||9||Will Brown||Holden Commodore ZB||15.317||6.300|
|5||6||Cameron Waters||Ford Mustang GT||15.533||0.216|
|6||5||James Courtney||Ford Mustang GT||15.772||0.239|
|7||20||Scott Pye||Holden Commodore ZB||16.233||0.462|
|8||18||Mark Winterbottom||Holden Commodore ZB||16.651||0.418|
|9||55||Thomas Randle||Ford Mustang GT||17.636||0.984|
|10||25||Chaz Mostert||Holden Commodore ZB||18.257||0.621|
|11||99||Brodie Kostecki||Holden Commodore ZB||19.603||1.346|
|12||26||David Reynolds||Ford Mustang GT||27.992||8.389|
|13||31||James Golding||Holden Commodore ZB||29.854||1.861|
|14||88||Broc Feeney||Holden Commodore ZB||36.488||6.634|
|15||2||Nick Percat||Holden Commodore ZB||36.800||0.313|
|16||14||Bryce Fullwood||Holden Commodore ZB||37.933||1.132|
|17||96||Macauley Jones||Holden Commodore ZB||38.187||0.254|
|18||3||Tim Slade||Ford Mustang GT||39.957||1.770|
|19||34||Jack Le Brocq||Holden Commodore ZB||40.957||1.000|
|20||4||Jack Smith||Holden Commodore ZB||43.674||2.717|
|21||35||Todd Hazelwood||Holden Commodore ZB||44.862||1.188|
|22||56||Jake Kostecki||Ford Mustang GT||45.409||0.547|
|23||8||Andre Heimgartner||Holden Commodore ZB||47.438||2.029|
|24||10||Lee Holdsworth||Ford Mustang GT||53.372||5.934|
|25||22||Chris Pither||Holden Commodore ZB|
|View full results|