Eddie O'Leary made around €400,000 from selling three horses at the Tattersalls October Yearling Sale on Tuesday.
O'Leary's Lynn Lodge Stud sold three yearlings for an average price of 131,667 guineas at the sale in Newmarket.
A Kodiac filly out of a Galileo mare made the most for the brother of Ryanair boss Michael O'Leary, going to Klaravich Stables for 160,000 guineas.
A Showcasing colt was purchased for 130,000 guineas by Manor House Stud, while an Invincible Spirit colt was bought by Powerstown Stud for 105,000 guineas.
Lynn Lodge Stud have seven more horses up for sale at the the Tattersalls Sale between Wednesday and Thursday.
Sheikh Mohammed and John Magnier were among those in attendance at the sale on Tuesday, while trainers Jessica Harrington, Joseph O'Brien and Donnacha O'Brien all made the trip over from Ireland.
At the same sale last year, Eddie O'Leary sold a Kingman filly out of a Dream Ahead dam for 1,450,000 guineas to flat racing powerhouse Godolphin.
Speaking at the time, he said: "She was always a Queen and made a Queen's price there. I hope she is very lucky for Sheikh Mohammed, she is a smashing filly."
Michael O'Leary continues to downsize his National Hunt racing empire and sold 39 horses for over €500,000 at the Goffs UK September Sale last month.
But the Ryanair boss admitted earlier this year that he can see himself buying horses again in the future.
He told Nick Luck on Racing TV's Luck on Sunday: "I'm very busy with the airline at the moment. My four children are keeping me very busy. And frankly my interests lie elsewhere for the next couple of years.
"But I am always fascinated with national hunt racing. Myself and Eddie have had a wonderful run for the last twenty years.
"I think we have won everything we set out to win. And I think now is the time for new owners to come through and take up that mantle and challenge JP McManus and all the other existing owners."
He added: "You never say never. I think certainly for the next ten years I will have almost no jumps horses in training.
"My youngest child is ten, so I think for the next ten years I will be largely focused on the children.
"After that, who knows? Would I like to have some jumps horses in the future? I think so."
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