Roads were sealed off and searched last night after residents reported hearing "loud bangs".
Officers were called to Muirhead Avenue, Clubmoor, at around 9.45pm on Monday to respond to reports of the noises.
They were called out to reports of mysterious "loud bangs" being heard by residents, before a black BMW drove away from the area.
Officers carried out house-to-house enquiries and photos from the scene showed a police presence in the area.
After extensive searches, police said there was no evidence of any firearms discharge and no one was found to be injured.
One ECHO reader who lives in the area but did not wish to be named told the ECHO: "[There was] an incident on Muirhead avenue last night - the road was blocked off by police between the roundabout and Queens Drive.
"A large section was taped off between the central reservation and the carriageway going towards Queens Drive. The other side was open.
"There must have been about six to seven police cars in between. I think it was about between 9.30 and 10.30"
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A spokesman for Merseyside Police said: "We are investigating after a report loud bangs were heard in Clubmoor last night (Monday 23 November).
"Just after 9.45pm, a report was received that bangs had been heard on Muirhead Avenue before a black BMW was seen driving away from the area.
"Officers attended and a search was conducted. No evidence has been found of any damage or firearm discharge, and no victims or anyone injured has been identified at this stage.
"House to house enquiries have been carried out and CCTV opportunities are being explored."
Anyone with information is asked to contact 101 with incident number 1026 of 23 November or Crimestoppers anonymously on 0800 555 111. Information can also be provided via their online form: https://crimestoppers-uk.org/give-information/give-information-online.
