David Moyes' West Ham Premier League XI has had a settled look to it so far this season with the Hammers so far coping admirably with their hectic schedule.
However, news of Angelo Ogbonna's ACL injury against Liverpool sees the manager required to make at least one alteration to his team to take on Wolves.
Recent injuries to Andriy Yarmolenko and Nikola Vlasic saw the West Ham squad stretched with little by way of attacking options available to Moyes off the bench against Liverpool. Both men are set to be available to Moyes this weekend, however, the full squad available to the manager is dependent on a number of international matches taking place on Tuesday with up to eight West Ham players involved for their countries.
Here, football.london has taken a look at the injury situation at the London Stadium by providing a round-up of all the players on the sidelines and their expected recovery time.
Angelo Ogbonna
West Ham's long term absentee Ogbonna is only at the start of what could be a lengthy spell on the sidelines after his ACL injury against Liverpool.
The best case scenario for Ogbonna is non-surgical treatment and a period of only two months out, however, should he require surgery the Italian's season would be effectively over.
Declan Rice
News of Declan Rice's withdrawal from the England squad was met with alarm by West Ham supporters. Fortunately for the Hammers faithful, it was only illness and not an injury that caused the midfielder to pull out of the Three Lions camp.
With 13 days between matches, Rice is expected to make a full recovery and be available for the trip to Molineux on Saturday.
Pablo Fornals
West Ham's Spanish international Pablo Fornals was a second half substitute for his country against Greece but was not included in the matchday squad for their second World Cup qualifier, the crunch clash with Sweden.
However, Fornals remained in Spain and was seen celebrating with his teammates as they secured passage to Qatar 2022. That Fornals did not return to Rush Green immediately suggests his issue is not a serious one that required him to seek medical treatment by the West Ham club doctors, with that in mind the attacking-midfielder is believed to be in contention for a start against Wolves.
Nikola Vlasic
West Ham's summer signing Nikola Vlasic missed the trip to Belgium and home game against Liverpool with a minor complaint and is back ready for action.
Vlasic started for Croatia against Russia in his nation's 1-0 win and providing he does not pick up a knock in their second international of the window on Tuesday evening the attacking-midfielder is expected to be part of Moyes' matchday squad against Wolves.
Andriy Yarmolenko
Ukraine captain Andriy Yarmolenko was in the same boat as Vlasic having missed the Hammers' last two matches. But as with the Croatian Yarmolenko took to the field for his country and came through unscathed.
With one international match remaining nothing is guaranteed when it comes to injury issues but at the time of writing the Hammers squad is in good health bar the unfortunate Ogbonna.
