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The Independent UK
The Independent UK
National
Vishwam Sankaran

Researchers perform a cross-species lung transplantation

  • Chinese scientists at Guangzhou Medical University have performed the world's first pig-to-human lung transplant.
  • The procedure involved transplanting a lung from a six-gene-edited pig into a 39-year-old brain-dead human recipient.
  • The pig's genes were modified to remove proteins that could activate the human immune system following transplantation.
  • The transplanted lung remained viable and functional for nine days, without immediate signs of hyperacute rejection or infection.
  • Although signs of damage and antibody-mediated rejection were observed, researchers are hopeful for long-term function with further genetic modifications and improved immunosuppressive drugs.

IN FULL

Scientists perform world’s first pig-to-human lung transplant

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