The Queen will talk to senior royals in private about Prince Harry and Meghan Markle's racism claims.
Buckingham Palace said in a statement that the issue - revealed in the couple's bombshell interview - will be "addressed privately".
The monarch is likely to have conversations with Prince Philip, Prince Charles and Prince William about the revelation.
Kate Middleton and Camilla, Duchess of Cornwall are also expected to be drawn into the probe.
Meghan claimed in her sit-down with Oprah Winfrey that a royal had asked about what colour her and Harry's unborn son Archie would be.
Got a story? Email webnews@mirror.co.uk.
But she refused to name the person, adding that it would be "damaging for them".
Harry also refused to give details, saying he was "shocked" by the conversation.
Meghan said the royal raised "concerns and conversations about how dark his [Archie's] skin might be when he's born".
Asked whether there were concerns that her child would be "too brown" and that would be a problem, she said: "If that is the assumption you are making, that is a pretty safe one."
The alleged remark has sparked debate around the world, with the source as-yet unidentified.
Winfrey ruled out the Queen and Prince Philip the day after the interview, claiming she had been told neither were involved.
The allegations of racism is just one of many issues to arise from the tell-all sit-down, but is the one noted by Buckingham Palace in a statement.
Released this evening, it said: "The whole family is saddened to learn the full extent of how challenging the last few years have been for Harry and Meghan.
"The issues raised, particularly that of race, are concerning. Whilst some recollections may vary, they are taken very seriously and will be addressed by the family privately.
"Harry, Meghan and Archie will always be much-loved family members."
A senior palace source added: "At the heart of all of this there is a family.
"They should be given the opportunity to discuss the issues raised privately, as a family.
"It has been important for us to carefully consider any response before issuing; and of course releasing something today meant viewers in the UK had the opportunity to watch the interview, if they wished to, first.
"Diversity, equality, inclusion and mental health are important issues and highlighting that has formed part of the work of Members of the Royal Family for many years."
Both Prince Charles and Prince William are said to be upset at having the finger of racism pointed at them.
The row has broken out while Prince Philip remains in hospital following an operation.
