Queensland's chief health officer hopes to see widespread home quarantine in the state by December, with a trial starting next week.
From Monday, 1000 people who have applied to enter Queensland from interstate hotspots have been offered the chance to go into 14 days of home, rather than hotel, quarantine.
The trial is only being offered to Queensland residents currently interstate, and will not be made available to those who opt to travel to hotspots.
Health chief Jeannette Young says if the trial is successful, widespread home quarantine could be implemented as soon as December.
"I hope to see (it), but let's wait, let's not jump ahead of ourselves," she told reporters on Thursday.
"We've got a trial starting on Monday with 1000 returning Queenslanders and we will see how that trial goes, but I would strongly recommend that anyone who would like to be part of the process going forward - go and get vaccinated because you need to have had two doses of vaccine, plus an extra two weeks (wait time for full efficacy).
"So as we gradually do look at this if it is successful, that will be one of the criteria."
Health Minister Yvette D'Ath said trial participants must have had at least two weeks since their second vaccination, a negative test 72 hours prior to travel and must reside within two hours of Brisbane airport.
"If you can't reside alone, then the whole household will need to quarantine. You will be bound by the testing and home quarantine checking system that we have put in place," the health minister added.
The government is still wary about home quarantine for international arrivals, and will closely monitor a trial in South Australia.
Ms D'Ath said mass quarantine facilities such as a state camp under construction near Toowoomba and a joint state-Commonwealth facility in Brisbane will be needed for many months to come for overseas workers and international students.
"They're not going to be made redundant, hopefully one day they will be redundant when it comes to COVID, but these facilities will be used for a whole lot of other things," she told reporters.
Currently, exemptions for home quarantine are only granted to certain students attending boarding schools in interstate hotspots, people with a disability and those recovering from medical procedures.
The home quarantine trial has been welcomed by thousands of Queenslanders stuck interstate, as well as people from other states who are trying to move to Queensland.
But Queensland's borders are set to stay closed to interstate virus hotspots until 80 per cent of eligible residents are fully vaccinated.
The Queensland government also wants to see the final analysis of measures used against the Delta variant of COVID-19 before reopening state borders.
Premier Annastacia Palaszczuk's office said the national cabinet of federal, state and territory leaders has only seen interim analyses of testing, tracing, isolation and quarantine measures, home quarantine trials and the impact of opening on local health networks.
"Queensland looks forward to seeing the completed advice from the Doherty Institute," a government official told AAP on Thursday.
Currently, 68.3 per cent of the state's population have had one dose of a vaccine and 49.53 per cent are fully vaccinated.
As Queensland passes five million vaccines administered, the state recorded zero locally acquired cases of COVID-19 on Thursday, while one was recorded in hotel quarantine and five in a bulk carrier off Cape York.
There are 31 active cases in Queensland.
