The two-week international break has its advantages and disadvantages for Premier League clubs with regards to the condition of their players before the next round of fixtures.
The positive for clubs is that it allows those already struggling with injuries and fitness to recover as best as they can in the absence of no matches for a fortnight.
However, it also means that those who have been selected for international duty are at risk of picking up injuries for their countries and becoming unavailable for their clubs upon their return to domestic action.
Here is all you need to know about the players who may be out of action upon the return of the Premier League this weekend.
Which team has had the worst luck with injuries this season? Have your say in the comments section.
Arsenal
Granit Xhaka remains a long-term absentee with a knee injury and isn’t expected back until late December as things stand, while Thomas Partey is recovering from a muscle injury but it is unclear as to when he will be fully fit again.
Sead Kolasinac picked up an ankle injury whilst playing for Bosnia-Herzegovina after being on the receiving end of a red card challenge and its seriousness is unclear, while Folarin Balogun was taken off for England U21s on Tuesday with stomach cramps.
The Gunners have 15 players away for internationals.
Aston Villa
Douglas Luiz (thigh/hamstring) is expected back after the international break but Bertrand Traore (thigh) and Trezeguet (knee) remain out with no current return date.
Danny Ings (Covid-19) and Ezri Konsa (suspension) are both expected to return as well.
Marvellous Nakamba may miss the first game back after picking up a groin strain whilst away with Zimbabwe.
10 of Villa ’s players are away for internationals.
Brentford
The Bees have had a tough time of late with injuries and there are no current return dates for Mads Sorensen (knee), David Raya (knee), Kristoffer Ajer (thigh), Mathias Jorgensen (muscular), Josh Dasilva (hip) and Shandon Baptiste (shoulder). Yoann Wissa (ankle) could return after the internationals but Mathias Jensen is self-isolating for Covid-19.
Thomas Frank has seven of his players away for internationals.
Brighton
Dan Burn (knee) and Aaron Connolly (heel) could make a return for Brighton ’s next game but Steven Alzate (foot) is out until the new year, while there are no return dates for Enock Mwepu (hamstring) and Danny Welbeck (thigh). Robert Sanchez is suspended.
The Seagulls have six first-team stars away for internationals.
Burnley
Sean Dyche has just two injury concerns as things stand. Aaron Lennon (illness) should return for the first game back but Dale Stephens (ankle) has no return date.
Seven Clarets are away for internationals.
Chelsea
Romelu Lukaku (ankle), Timo Werner (thigh), Mateo Kovacic (thigh) and Marcos Alonso (ankle) are all expected to return after the internationals, while Mason Mount (dental) is still being assessed after missing the internationals with England.
13 Chelsea first-team stars are away for internationals.
Crystal Palace
Will Hughes (back) is set to return after the internationals but Eberechi Eze (fitness) and Nathan Ferguson (calf) are still in the process of recovery.
Joachim Anderson is currently being assessed since leaving international duty with Denmark after failing to recover from a minor injury.
The Eagles have seven first team players away for internationals.
Everton
Yerry Mina (thigh) could return this weekend but Andre Gomes (thigh) and now Tom Davies (knee) will remain out.
Abdoulaye Doucoure (ankle) and Dominic Calvert-Lewin (thigh) are expected back at the start of December. Mason Holgate is suspended until the following week.
Everton have 10 players away for internationals.
Leeds
It is hoped that Junior Firpo (unknown), Jamie Shackleton (unknown), Joe Gelhardt (unknown), Luke Ayling (knee) and Patrick Bamford (ankle) will all return on November 21, but Robin Koch (groin) will be out until next month.
15 Leeds players are away for internationals.
Leicester
The Foxes currently have five players in the treatment room but Marc Albrighton (unknown) and James Justin (knee) could return at the end of the month.
Wesley Fofana (ankle) is out until the new year and there is no current return date for Ryan Bertrand (knee) or Youri Tielemans (calf).
Leicester have 11 players away for internationals.
Liverpool
The Reds have the highest injury list in the league, with nine players receiving treatment, but James Milner (thigh), Naby Keita (thigh) and Joe Gomez (calf) could return this weekend, along with Sadio Mane (chest) and Jordan Henderson (fitness) who picked up minor injuries whilst away.
Andrew Robertson picked up a muscle injury whilst representing Scotland in the week so could miss Liverpool's game with Arsenal but Roberto Firmino (thigh) will be out for a few more weeks, as will Curtis Jones (eye), while Harvey Elliot (ankle) is progressing with his long-term rehabilitation.
Jurgen Klopp has 14 players away for internationals.
Manchester City
City have three injury worries as things stand. There is no return date for Liam Delap (ankle) but Jack Grealish (unknown) is being assessed after leaving the England camp as a precaution.
Ferran Torres (ankle) will be out until the new year but Aymeric Laporte will return this weekend from suspension.
The club has 20 players away for internationals.
Manchester United
Five United players are currently missing but only Raphael Varane (thigh) has a return date - December at the earliest.
Paul Pogba (thigh), Edinson Cavani (tendon) and Luke Shaw (concussion) are all being assessed, along with Scott McTominay (illness) who was sent home from the Scotland camp with a throat virus, but he should be available for the trip to Watford on Saturday.
United have 10 players away for internationals.
Newcastle
The Magpies have just two injuries - Ryan Fraser (knock) is expected to come back this weekend but there is no current return date for Paul Dummett (calf).
Seven players are away for internationals.
Norwich
New Norwich boss Dean Smith is without seven players as things stand but Ozan Kabak (fever) and Grant Hanley (groin) could return this weekend.
Todd Cantwell (unknown), Sam Byram (thigh) and Christoph Zimmermann (ankle) are out for longer, while Andrew Omobamidele (achilles) and Billy Gilmour (muscular) are being assessed after playing for the Republic of Ireland and Scotland, respectively.
The club have 11 players away for internationals.
Southampton
The Saints are without four players and await return dates for Valentino Livramento (knock) and Jack Stephens (knee), but Nathan Redmond (Covid-19) and James Ward-Prowse (illness) should make a quick return.
Armando Broja is having further assessment for an ankle injury.
Southampton have seven players away for internationals.
Tottenham
Antonio Conte has three injury concerns as Bryan Gil (thigh) and Ryan Sessegnon (thigh) are out of the side but it is unclear as to when they’ll return. Oliver Skipp is suspended until next weekend.
Pierre-Emile Hojbjerg (knee) is currently being assessed after an injury picked up on international duty with Denmark, along with Cristian Romero (hamstring) who was taken off in Argentina's game with Brazil on Tuesday.
Spurs have 14 first-team stars away for internationals.
Watford
The Hornets have four injuries to deal with as things stand and Christian Kabasele (thigh), Ken Sema (knee) and Kwadwo Baah (ankle) will hope to return soon but Peter Etebo (thigh) is out until March 2022. Juraj Kucka's (suspension) red card against Arsenal means he misses out for another week.
Nine of Claudio Ranieri’s side are away for internationals.
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West Ham
David Moyes can expect his three sidelined players to make a return after the international break. Angelo Ogbonna (head), Pablo Fornals (knock) and Declan Rice (illness) are on the road to recovery and could all feature this weekend.
The Hammers have 11 players away for internationals.
Wolves
Fernando Marcal (calf) should be fit to return at the end of the month but Johnny Otto (knee), Pedro Neto (knee), Yerson Mosquera (thigh) and Hugo Bueno (thigh) remain out.
Wolves have 12 players away for internationals.
