The fire at Cribbs Causeway's Premier Inn hotel has led to the closure of a major road.
The A4018 (Cribbs Causeway Road) is closed to all traffic in both directions between Clifton Rugby Club and Lysander Road. All bus services are being diverted.
First Bus has tweeted: "Due to a fire road closed in both directions between Clifton Rugby Club and Lysander Rd in both directions.
"Services 1, 2, 3, & 4 are terminating at Crow Lane. There will be shuttle services providing the link from Crow Lane and Cribbs.
"Shuttle service going via Hayes Rd, A38, Southmead Rd, Pen Park Road & Knole Lane in both directions.
"Unable to serve Station Road and Wyck Beck Rd until further notice."
The fire started on the third floor at around 1.20pm. It has spread to the roof, causing black smoke to billow, visible from miles away.
Avon Fire and Rescue Service has warned people living nearby to close their doors and windows due to large amounts of smoke.
You can follow our live coverage of the ongoing fire here.
In other news, Extinction Rebellion protesters have blocked the M32 in the city centre. One protester has used superglue to attach themselves to a pink bathtub which is blocking the road - police have made multiple arrests at the scene.
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