All eyes will be on whether Mauricio Pochettino changes a winning side once again as Tottenham Hotspur return to Premier League action.
Spurs impressed in a 4-0 victory at Red Star Belgrade in the Champions League on Wednesday night, but the manager often rotates his team after midweek matches.
He also hinted that changes might have to be made because of 'small injuries' to certain players who took part in the game in Serbia.
There will be plenty of disgruntled Spurs fans if Giovani Lo Celso drops down to the bench after dazzling on his full debut, but Pochettino could be wary of playing the 23-year-old Argentine twice with just two days in between after making his first start in four months.
He told football.london after the match that Lo Celso would have to be assessed in the days after the game, having got 85 minutes under his belt.
His likely replacement would be Eriksen, who also scored on Wednesday night but is still struggling for form, and that would also prove to be an unpopular call.
There will be changes in the defence. Toby Alderweireld, Serge Aurier and Ben Davies could all come into the back line despite the back four keeping a clean sheet in midweek.
Aurier and Harry Winks, along with Kyle Walker-Peters and Victor Wanyama, did not travel to Serbia.
Ryan Sessegnon did make his Champions League debut on Wednesday, laying on the goal for Eriksen, while Oliver Skipp also made his bow in the competition.
Erik Lamela, Jan Vertonghen and Hugo Lloris remain out injured while young striker Troy Parrott, who was called up on to senior Ireland squad this week could also make his second consecutive appearance on a Premier League match day bench depending on how many have picked up injuries.
Here is the team we reckon will start against a battling Sheffield United side.
(4-2-3-1) Gazzaniga; Aurier, Alderweireld, Sanchez, Davies; Winks, Ndombele; Lo Celso, Eriksen, Son; Kane.
