FA Cup fixtures often lead to wholesale changes for Man City, especially against lower league opposition.
However, following Thursday's press conference which saw assistant Rodolfo Borrell announce that seven players were among the 21 isolating due to Covid, the City team will be hard to predict.
Pep Guardiola will be among those missing the trip to Wiltshire after he tested positive for the virus.
No doubt he will be watching along from home to see if any players can catch his eye.
Assuming all of these men are fit you would imagine that Zack Steffen will start in goal due to it being the FA Cup.
Kyle Walker is likely to feature for his first start since the beginning of December with John Stones, Luke Mbete and Josh Wilson-Esbrand making up the back four.
In midfield there is a chance for more youngsters to impress with James McAtee worthy of a start against opposition similar to those he has faced in the EFL Trophy this campaign.
Cole Palmer is also likely to start up front if healthy, while Jack Grealish may also feature in a bid to find his footing again since being dropped by Guardiola.
Predicted City XI vs Swindon Town: Steffen; Walker, Stones, Mbete, Wilson-Esbrand; Lavia, Gundogan, McAtee; Palmer, Jesus, Grealish
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