Popular options at fast food restaurants including the Quarter Pounder meal, Whopper meal and KFC Mighty Bucket could be under threat.
A major new report released to the Government has called for a range of measures to cut obesity in the UK, meaning the above meals and others could be scrapped under a "calorie cap".
Other measures include expanding the sugar tax currently imposed on soft drinks, banning food on public transport, banning unhealthy food from sports venues and placing a cap on the number of calories allowed in a restaurant meal.
The report has been written by outgoing chief medical officer Dame Sally Davies, who is urging the government to force cafés, pubs and takeaways to axe high-calorie burgers, chicken dishes and pizzas, reports The Daily Star.
In her final report as CMO for England, the top doctor says she wants to tackle child obesity and says ministers must put health before profits.
Her hard-hitting report includes proposals for a cap on calories per serving of food and drink in eateries.
The limit is likely to be set at around 951 calories, in line with Public Health England recommendations.
But many meals contain far higher calorie counts and would face the chop, including a Nando’s 1/2 medium chicken, regular peri salted chips and peas at 1,185 calories.
A McDonald’s double quarter pounder with cheese and large fries meal (1,194 calories) would also be out, as would KFC’s Mighty Bucket For One (1,235 calories).
UK Hospitality chief executive Kate Nicholls said: "A blanket cap on calories for all portions of food and drink consumed out-of-home sounds like a knee-jerk and unfair measure."
